Tramal (Long / Plus / SR / Retard)

Tramal (Long / Plus / SR / Retard)

Tramadol, marketed as Tramal, is an opioid analgesic medication used to treat moderate to moderately severe pain. The active pharmaceutical ingredient (API) of this pain medicine was patented over 50 years ago and first released as the branded pharmaceutical, Tramal.

After its approval in the UK and the U.S in the mid-1990's, these painkiller tablets became widely used for the management of pain symptoms. In fact, this pain-reliever was the 25th most frequently used medication, according to statistics from three years ago, recording a total of 24 million prescriptions.

In the UK, a survey from last year reported that approximately 16% of people above the age of 16 years were thought to be affected by chronic pain. This percentage increased to 38%, for those of the same age group, who experienced noticeable pain at least once a day. With such high percentages of the local population affected by the discomfort of pain, it is understandable that many adults buy painkillers in the UK via convenient online pharmacies. This includes Tramal as a popular and frequent brand option.

You can buy tramadol in the UK through our reputable online pharmacy, in immediate-release and extended-release capsules. Alternatively, there are intravenous (injected into a vein) and intramuscular (injected into a muscle) injections available for fast-acting relief from pain.

What is Tramal?

Tramal is an opiate analgesic. This means that is a medication with strong pain-relieving properties and functions by interacting with opioid receptors to mask painful sensations.

The analgesic effects of this medication are equal in potency to that of codeine and pethidine, and are thought to be about one-tenth of the potency of morphine, on a dose-by-dose basis according to the World Health Organisation (WHO). When taken through the oral route, the pain relief can be effective for the management of both acute and chronic pain too. Some of the medical conditions relieved by this medication are chronic back pain and acute post-operative pains.

These painkiller pills can also be used as a second-line treatment of fibromyalgia, which is a painful musculoskeletal condition known to affect the entire body. The cause of this disorder is unknown but it is believed that fibromyalgia may be due to the manner in which the brain and spinal cord process painful and non-painful sensations. The UK National Health Services (NHS) approves the use of Tramal as a secondary treatment option for fibromyalgia.

Tramal Active Ingredient

An API is the part of a medication that brings forth the therapeutic effects. The API of Tramal tablets is tramadol hydrochloride.

These analgesic tablets can be formulated as:

  • Immediate-release: also known as fast-acting, immediate-release Tramal dissolves or disperses the API rapidly, once the medicine is administered. This formulation is appropriate for situations where pain relief is required quickly and for a short duration as well.
  • Extended-release: the extended-release forms of this painkiller release the API in a bi-phasic manner. The bi-phasic formulation releases 25% of the medication within two hours of administration and the remaining 75% over a 24 hour period. The slow-release form can be used for prolonged relief from pain, such as when managing the symptoms of fibromyalgia. The analgesic effects of these pills typically take longer to come into prominence when compared to the immediate-release tablets.

Tramal Duration of Effects

  • As previously mentioned, the immediate-release formulations of Tramal have a shorter duration of action than the extended-release capsules. These pills can relieve pain for about four to six hours, when administered by mouth.
  • The slow-acting forms of this analgesic release the API steadily so as to extend pain relief. Those who require prolonged duration of therapeutic action can buy tramadol 50 mg in extended-release formulations, as these pills can take effect for approximately 24 hours, or longer in some situations.
  • The duration of therapeutic effects of Tramal is dependent on an individual's genetics. The medicine may not provide adequate pain relief for those with genetic variants of CYP2D6 enzymes, as these persons generally metabolise (breakdown) the therapeutic to the inactive metabolite, rather than the active metabolite required for analgesia.
  • These pain-reliever pills can also be formulated with other analgesics for longer duration of action or more potent pain relieving effects.

Tramal Dosage Instructions

  • A 50mg to 100mg dosage of the immediate-release capsules can be administered, every four to six hours, for the relief of pain. For most patients, an initial 25mg dose should be administered when you begin treatment and this can be titrated in 25mg increments, every three days, based on your response and tolerance to the medication.
  • The immediate-release Tramal tablets should be swallowed with a glass of water and can be taken with or without food.
  • For adults using the extended-release pills for the relief of chronic pain, a 100 mg dosage should be administered only once a day.
  • It is essential that when using the slow-release forms of Tramal, that one does not chew or crush the medication as this may release the API all at once. These tablets are designed to dissolve in a particular manner so as to release the API slowly and prolong pain relief.
  • Tramal dosage selection should be cautious for senior patients as they are susceptible to adverse effects. Elderly patients should administer the lowest possible dose for the relief of pain so as to minimise the risk of side effects.
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Some Tramal Side Effects

Tramal is usually well-tolerated by those who take the medicine and the side effects of this medication are generally transient. Among those adverse effects experienced by 5% or more of patients are:

  • Constipation
  • Headaches
  • Vomiting
  • Drowsiness
  • Sweating
  • Diarrhoea
  • nausea

Among the adverse effects experienced by less than 5% of patients taking the medication are:

  • Weight loss
  • Fainting
  • Visual disturbances
  • Rapid heartbeats
  • Confusion
  • Lack of co-ordination

Those Tramal side effects that require immediate medical attention include:

  • Allergic reactions
  • Respiratory difficulties

Are Opioid Analgesics Like Tramal Safe for Everyone?

Tramal has been used medically in Germany since the late 1970's and is typically not related to serious cardiovascular or respiratory adverse events. These painkiller tablets normally have low incidences of cardiac depression and are known to cause less drowsiness and dizziness than other opioid analgesics, such as morphine. It has also been reported that the abuse potential and dependence of Tramal is negligible (Lehmann, 1997).

However, when you buy painkillers online, you should be aware of the side effect profile as well as the potential for dependence and tolerance before using the medicine. Though they are safe, opiates, such as these painkillers, still carry a risk for misuse, especially when using the therapeutic in the long-term.

Tramal may cause dependence and tolerance when administered in dosages higher than those advised or when used for treatment periods longer than those recommended. To remain safe when using this analgesic, you should use the medication exactly as directed.

More About the Usage of Tramal in the UK

Chronic pain is believed to affect about one-third to one-half of the UK adult population. Research shows that among all the regions in the UK, those in the Yorkshire and the North West regions were reported to be affected by chronic pain on a greater scale, than people of any other region in the UK, according to a 2020 survey. This correlates to a study conducted by Jani et. al. (2020) which revealed that these regions, in conjunction with the South West regions of England, were among those with a higher risk of long-term opiate use.

As part of the most frequently researched Google topics in the UK was the medical condition, fibromyalgia and the symptoms thereof. The NHS has estimated that at least one in 20 adults are affected by this widespread musculoskeletal discomfort in the Europe, which may be a possible explanation for the popularity of this disorder among Google search results.

You can easily purchase Tramal pain tablets in the UK, or any other location, through our secure online pharmacy.

Buy Tramal Opioid Analgesic Painkillers

According to DataRePortal, an online service that offers reports of internet usage, the population of the United Kingdom stood at 68.05 million as of the beginning of this year. Of this population, there were approximately 65.32 million internet users as per January 2021.

This number of internet users increased by 325 thousand from last year to this year, which is an indication that more and more people are comfortable with using online platforms for various services, including the buying of medications.

We offer the retail of a wide range of FDA-approved medications, from trusted branded options to affordable bioequivalent generic medications. Generics are the same as a brand name medicine, except that it may differ in aspects not relating to the efficacy of the therapeutic, such as the packaging.

Anyone can make use of our website as it is easy to navigate, but our internet pharmacy is especially useful for those suffering from painful chronic symptoms. Furthermore, when buying from our online pharmacy, you can have your healthcare products delivered right to your doorstep, which means that you do not have to travel to buy your pain-relieving medicines.

Buy Tramal painkillers today and get fast and effective pain relief. The process is fast and script free/paperless, with customer service available day and night to further assist.

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Nina Simmons – Jun 27, 2021
Having recently been immobilized due to a bad accident I have found this article to be extremely helpful. Ordering online has been the icing on the cake and saved me so much bother. Thank you. Nina Simmons

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